Yicong Li

Yicong_Little_Havana.png

Little Havana, 2025

I’m a Ph.D. candidate in Computer Science at Harvard University, advised by Prof. Hanspeter Pfister in Visual Computing Group (VCG), with an M.S. in Bioengineering. I also work with Prof. Jeff W. Lichtman, Prof. Aravinthan D.T. Samuel, Prof. Dmitri “Mitya” B. Chklovskii, Prof. Jingpeng Wu, Prof. Bill Lotter, and Prof. Wanhua Li.

Previously, I obtained my master’s degree from Tsinghua University advised by Prof. Yang Li and my bachelor’s degree from Sichuan University’s Wu Yuzhang Honors College. During this period, I was fortunate to work with Prof. Nir Shavit and Prof. Lu Mi at MIT CSAIL, and Prof. Faisal Mahmood at Harvard Medical School.

I interned at Netflix, Genentech, Microsoft Research (with Dr. Kristen Severson), Simons Foundation’s Flatiron Institute, and Huawei (with Prof. Nanshan Zhong’s team).

I aim to develop bleeding-edge AI techniques to address important real-world challenges. My recent work explores:

  • Vision-Language Model Post-Training: supervised fine-tuning, reinforcement learning, in-context learning, and synthetic data generation.
  • Self-Evolving Agentic Systems: automatic prompt/skill/workflow/harness optimization.
  • Computer Vision: 2D & 3D image segmentation/restoration/compression, object detection, self-supervised learning, and vision foundation models.
  • Generative Models: VAEs, GANs, and diffusion models.
  • AI for Neuroscience: large-scale electron microscopy image analysis for connectomics.
  • AI for Healthcare: computational pathology, respiratory disease screening and quality assurance, embryo viability prediction in IVF, and MRI/CT/X-ray image analysis.

I’m a recipient of the Laverack Family Innovation Fund Fellowship in the Division of Engineering and Applied Sciences from Harvard University and the prestigious (only 5) “Wang Wen Guo” scholarship from Sichuan University. My research has been featured in MIT News, Forbes, MarkTechPost, Computer Vision News, and ERCIM News.

I'm currently on the industry job market — feel free to reach out!



Selected Publications

  1. chen2022scaling.PNG
    Scaling Vision Transformers to Gigapixel Images via Hierarchical Self-Supervised Learning
    Richard J. Chen, Chengkuan Chen, Yicong Li, Tiffany Y. Chen, Andrew D. Trister, Rahul G. Krishnan, and Faisal Mahmood
    In Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2022
    Oral
  2. wang2022deep.PNG
    Deep learning for spirometry quality assurance with spirometric indices and curves
    Yimin Wang*, Yicong Li*, Wenya Chen, Changzheng Zhang, Lijuan Liang, Ruibo Huang, Jianling Liang, Dandan Tu, Yi Gao, Jinping Zheng, and Nanshan Zhong
    Respiratory Research, 2022
  3. 10230759.PNG
    X-Ray2EM: Uncertainty-Aware Cross-Modality Image Reconstruction from X-Ray to Electron Microscopy in Connectomics
    Yicong Li, Yaron Meirovitch, Aaron T. Kuan, Jasper S. Phelps, Alexandra Pacureanu, Wei-Chung Allen Lee, Nir Shavit, and Lu Mi
    In IEEE 20th International Symposium on Biomedical Imaging (ISBI), 2023
  4. li2022finding.PNG
    Finding the Most Transferable Tasks for Brain Image Segmentation
    Yicong Li, Yang Tan, Jingyun Yang, Yang Li, and Xiao-Ping Zhang
    In IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2022
  5. li2021does.PNG
    How Does Policy Stringency Affect the Spread of COVID-19 Pandemic? A Country Level Study
    Yicong Li*, Calvin Chan*, Yang Li, and Ercan Engin Kuruoglu
    In 29th European Signal Processing Conference (EUSIPCO), 2021
    Oral
  6. meirovitch2025smartem.PNG
    SmartEM: Machine-Learning Guided Electron Microscopy
    Yaron Meirovitch*, Ishaan Singh Chandok*, Core Francisco Park*, Pavel Potocek*, Lu Mi, Shashata Sawmya, Yicong Li, Thomas L. Athey, Vladislav Susoy, Neha Karlupia, Yuelong Wu, Daniel R. Berger, Richard Schalek, Caitlyn A. Bishop, Daniel Xenes, Hannah Martinez, Jordan Matelsky, Brock A. Wester, Hanspeter Pfister, Remco Schoenmakers, Maurice Peemen, Jeff W. Lichtman, Aravinthan D.T. Samuel, and Nir Shavit
    2025
    Nature Methods
  7. li2024waspsyn.PNG
    WASPSYN: A Challenge for Domain Adaptive Synapse Detection in Microwasp Brain Connectomes
    Yicong Li, Wanhua Li*, Qi Chen*, Wei Huang*, Yuda Zou*, Xin Xiao*, Kazunori Shinomiya, Pat Gunn, Nishika Gupta, Alexey Polilov, Yongchao Xu, Yueyi Zhang, Zhiwei Xiong, Hanspeter Pfister, Donglai Wei, and Jingpeng Wu
    IEEE Transactions on Medical Imaging, 2024
  8. li2024compressor.PNG
    EM-Compressor: Electron Microscopy Image Compression in Connectomics with Variational Autoencoders
    Yicong Li, Core Francisco Park, Daniel Xenes, Caitlyn Bishop, Daniel R. Berger, Aravi D.T. Samuel, Brock Wester, Jeff W. Lichtman, Hanspeter Pfister, Wanhua Li, and Yaron Meirovitch
    In 27th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI) Workshop, 2024
  9. li2025correcting.PNG
    Correcting Non-Uniform Milling in FIB-SEM Images with Unsupervised Cross-Plane Image-to-Image Translation
    Yicong Li*, Yuri Kreinin*, Siyu Huang, Lewei Zhang, Erik W. Schomburg, Dmitri B. Chklovskii, Hanspeter Pfister, and Jingpeng Wu
    bioRxiv, 2025
  10. yang2021joint.PNG
    Joint PVL Detection and Manual Ability Classification Using Semi-Supervised Multi-Task Learning
    Jingyun Yang, Jie Hu, Yicong Li, Heng Liu, and Yang Li
    In International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2021
  11. tan2023efficient.PNG
    Efficient Prediction of Model Transferability in Semantic Segmentation Tasks
    Yang Tan, Yicong Li, Yang Li, and Xiao-Ping Zhang
    In 2023 IEEE International Conference on Image Processing (ICIP), 2023
  12. yang2023investigating.PNG
    Investigating Consistency Constraints in Heterogeneous Multi-Task Learning for Medical Image Processing
    Jingyun Yang, Yicong Li, Yang Tan, Heng Liu, and Yang Li
    In 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Workshop, 2023
  13. shi2024mora.PNG
    MoRA: LoRA Guided Multi-Modal Disease Diagnosis with Missing Modality
    Zhiyi Shi, Junsik Kim, Wanhua Li, Yicong Li, and Hanspeter Pfister
    In International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2024
    Early Acceptance
  14. kim2024multimodal.PNG
    Multimodal Learning for Embryo Viability Prediction in Clinical IVF
    Junsik Kim, Zhiyi Shi, Davin Jeong, Johannes Knittel, Helen Y. Yang, Yonghyun Song, Wanhua Li, Yicong Li, Dalit Ben-Yosef, Daniel Needleman, and Hanspeter Pfister
    In International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2024
  15. yang2025towards.PNG
    Towards 1000-Fold Electron Microscopy Image Compression for Connectomics via VQ-VAE with Transformer Prior
    Fuming Yang, Yicong Li, Hanspeter Pfister, Jeff W. Lichtman, and Yaron Meirovitch
    In IEEE 23rd International Symposium on Biomedical Imaging (ISBI), 2026
  16. li2022lidar.PNG
    LiDAR Integrated IR OWC System with Abilities of User Localization and High-Speed Data Transmission
    Zhi Li, Yicong Li, Zihan Zang, Yaqi Han, Lican Wu, Mutong Li, Qian Li, and HY Fu
    Optics Express, 2022